Meet Dr. Derbala

Dr. Youssef Derbala is an Obstetrician and Gynecologist, specialized in reproductive immunology. He is board certified by the American Board of Obstetrics and Gynecology (ABOG) and the American Society of Reproductive Immunology (ASRI). He graduated from Cairo university school of medicine.

Dr. Derbala had a great opportunity to complete 2 years of NIH research fellowship at Perinatology Research Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) where he was mainly studying pregnancy-related complications such as preterm labor, preeclampsia, fetal growth restriction, and many other conditions.

Reproductive immunology has been his main interest since he graduated from the OBGYN residency program at Wayne state university in Detroit, Michigan. He completed 2 years of clinical fellowship training in reproductive medicine and immunology at Rosalind Franklin University of medicine and science in North Chicago, Illinois. During his fellowship, Dr. Derbala gained great experience in treating women with recurrent pregnancy loss, unexplained infertility, multiple IVF failures and other immunological disorders complicating the pregnancy.

Dr. Youssef Derbala
Dr. Youssef Derbala (Obstetrician and Gynecologist)

Medical Education and Training

2016-2018

Clinical Fellowship (Reproductive Medicine and Immunology)

Chicago Medical School / Rosalind Franklin University of Medicine and Science,North Chicago, Illinois

2012-2016

Residency (Obstetrics and Gynecology)

Wayne State University School of Medicine / Detroit Medical Center,

Detroit, Michigan

2010-2012

Research Fellowship (Perinatology Research Branch)

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institute of Health (NIH)

2006-2010

Residency (Obstetrics and Gynecology)

El Galaa Maternity Hospital / Cairo University School of Medicine, Cairo, Egypt

2005-2006

Internship Training

Cairo University School of Medicine, Cairo, Egypt

1998-2004

Medical Degree (M.D.)

Cairo University School of Medicine

Publications, Abstracts and Book Chapter

  1. Derbala Y, Elazzamy H, Bilal M, Reed R, Salazar Garcia MD, Skariah A, Dambaeva S, Fernandez E, Germain A, Gilman-Sachs A, Beaman K, Kwak-Kim J. Mast cells-induced immunopathology in recurrent pregnancy losses. Am J Reprod Immunol. 2019 April; 2019 Jul;82(1):e13128.
  2. Kwak-Kim J, Ota K, Sung N, Huang C, Alsubki L, Lee S, Han JW, Han A, Yang X, Saab W, Derbala Y, Wang WJ, He Q, Liao A, Takahashi T, Cavalcante MB, Barini R, Bao S, Fukui A, Lédée N, Coulam C. COVID-19 and immunomodulation treatment for women with reproductive failures. J Reprod Immunol. 2020 Sep;141:103168.
  3. El-Azzamy H,Dambaeva SV, Katukurundage D, Salazar Garcia MD, Skariah A, Hussein Y, Germain A, Fernandez E, Gilman-Sachs A, Beaman KD, Kwak-Kim J. Dysregulated uterine natural killer cells and vascular remodeling in women with recurrent pregnancy losses. Am J Reprod Immunol. 2018 Oct;80(4): e13024.
  4. Gilman-Sachs A, Dambaeva S, Salazar Garcia MD, Hussein Y, Kwak-Kim J, Beaman K. Inflammation induced preterm labor and birth. J Reprod Immunol. 2018 Sep; 129:53-58.
  5. Soto E, Romero R, Kusanovic JP, Ogge G, Hussein Y, Yeo L, Hassan SS, Kim CJ, Chaiworapongsa T. Late-onset preeclampsia is associated with an imbalance of angiogenic and anti-angiogenic factors in patients with and without placental lesions consistent with maternal underperfusion. J Matern Fetal Neonatal Med. 2012 May;25(5):498-507.
  6. Romero R, Chaiworapongsa T, Savasan ZA, Xu Y, Hussein Y, Dong Z, Kusanovic JP, Kim CJ, Hassan SS. Damage-associated molecular patterns (DAMPs) in preterm labor with intact membranes and preterm PROM: a study of the alarmin HMGB1. J Matern Fetal Neonatal Med. 2011 Dec;24(12):1444-55.
  7. Ogge G, Chaiworapongsa T, Hussein Y, Kusanovic JP, Yeo L, Kim CJ, Hassan SS, Romero R. Placental lesions associated with maternal underperfusion are more frequent in early-onset than in late-onset preeclampsia. J Perinat Med. 2011 Nov;39(6):641-52.
  8. Romero R, Chaiworapongsa T, Savasan ZA, Xu Y, Hussein Y, Dong Z, Kusanovic JP, Kim CJ, Hassan SS. Clinical chorioamnionitis is characterized by increased expression of the alarmin HMGB1 and One of Its Receptors, sRAGE. J Matern Fetal Neonatal Med. 2012 Jun;25(6):558-67.
  9. Savasan ZA, Chaiworapongsa T, Romero R, Hussein Y, Kusanovic JP, Xu Y, Dong Z, Kim CJ, Hassan SS. IL-19 in Fetal Systemic Inflammation. J Matern Fetal Neonatal Med. 2012 Jul;25(7):995-1005.
  10. Hernandez-Andrade E, Romero R, Ahn H, Hussein Y, Yeo L, Korzeniewski SJ, Chaiworapongsa T, Hassan SS. Transabdominal evaluation of uterine cervical length during pregnancy fails to identify a substantial number of women with a short cervix. J Matern Fetal Neonatal Med. 2012 Sep;25(9):1682-9.
  11. Hernandez Andrade E, Hussein Y, Ahn H, Chaiworapongsa T, Whitten A, Hassan SS, Romero R.Estimation of blood perfusion using two and three-dimensional power Doppler ultrasound derived techniques. 22nd World Congress on Ultrasound in Obstetrics and Gynecology. Copenhagen, Denmark, September 2012. Ultrasound Obstet Gynecol, 2012, Vol.40 (S1)
  12. Patwardhan M, Ahn H, Hernandez Andrade E, Korzeniewski S, Hussein Y, Tang X, Chaiworapongsa T, Hassan SS, Romero R. Dynamic myometrial changes in the upper and lower uterine segments during the third stage of Labor. 22nd World Congress on Ultrasound in Obstetrics and Gynecology. Copenhagen, Denmark, September 2012. Ultrasound Obstet Gynecol, 2012, Vol.40 (S1). (Award winner Best short oral presentation in Labor)
  13. Feldman DS, Hussein Y, Kwon S, Nguyen K, Salazar Garcia MD, Skariah A, Kwak-Kim J. MTHFR C677T and A1298C gene polymorphisms as risk factors for recurrent pregnancy loss and repeated implantation failure. 37th Annual Meeting of American Society of Reproductive Immunology. Chicago, IL, USA September 2017 (Poster Presentation).
  14. Salazar MD, Skariah A, Hussein Y, Elazzamy H, Dambaeva S, Beaman K, Gilman-Sachs A, Kwak-Kim J. Association between endometrial and peripheral blood immune profiles and reproductive outcome in patients with recurrent pregnancy loss (RPL) and repeated implantation failure (RIF). 37th Annual Meeting of American Society of Reproductive Immunology. Chicago, IL, USA September 2017 (Poster Presentation).
  15. Elazzamy H, Dambaeva S, Salazar MD, Skariah A, Hussein Y, Gilman-Sachs A, Beaman K, Kwak-Kim J. Uterine NK cells play a key role in the vascular transformation of endometrium. 37th Annual Meeting of American Society of Reproductive Immunology. Chicago, IL, USA September 2017 (Poster Presentation).
  16. Elazzamy H, Dambaeva S, Katukurundage D, Salazar MD, Skariah A, Hussein Y, Germain A, Fernández E, Gilman-Sachs A, Beaman K, Kwak-Kim J. Uterine NK Cells Play a Key Role in the Vascular Transformation of Endometrium. 65th Annual scientific meeting of Society of Reproductive Investigations. San Diego, CA, USA March 2018 (Poster Presentation).
  17. Salazar Garcia M, Reed R, Hussein Y, Elazzamy H, Skariah A, Dambaeva S, Gilman-Sachs A, Beaman K, Kwak-Kim J. Peripheral Blood NK Cytotoxicity Levels as a Biomarker in Non-Pregnant and Pregnant Women with Reproductive Failure. 65th Annual scientific meeting of Society of Reproductive Investigations. San Diego, CA, USA March 2018 (Oral Presentation).
  18. Book Chapter: Salazar MD, Sung N, Kim A, Hussein Y, Elazzamy H, Kwak-Kim “Plasminogen Activator Inhibitor-1 and Reproduction” Plasminogen activator biosynthesis and role in disease. Nova science publisher, New York, 2018. In Press

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